Impact of Promoter Polymorphisms on the Transcriptional Regulation of the Organic Cation Transporter OCT1 (SLC22A1)

The organic cation transporter 1 (OCT1, SLC22A1) is strongly expressed in the human liver and facilitates the hepatic uptake of drugs such as morphine, metformin, tropisetron, sumatriptan and fenoterol and of endogenous substances such as thiamine. OCT1 expression is inter-individually highly variab...

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Detalles Bibliográficos
Autores principales: Bokelmann, Kristin, Brockmöller, Jürgen, Tzvetkov, Mladen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313513/
https://www.ncbi.nlm.nih.gov/pubmed/30544975
http://dx.doi.org/10.3390/jpm8040042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313513/
https://www.ncbi.nlm.nih.gov/pubmed/30544975
http://dx.doi.org/10.3390/jpm8040042

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