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New Insights into Development of Transglutaminase 2 Inhibitors as Pharmaceutical Lead Compounds
Transglutaminase 2 (EC 2.3.2.13; TG2 or TGase 2) plays important roles in the pathogenesis of many diseases, including cancers, neurodegeneration, and inflammatory disorders. Under normal conditions, however, mice lacking TGase 2 exhibit no obvious abnormal phenotype. TGase 2 expression is induced b...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313797/ https://www.ncbi.nlm.nih.gov/pubmed/30297644 http://dx.doi.org/10.3390/medsci6040087 |