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Challenges in Stratifying the Molecular Variability of Patient-Derived Colon Tumor Xenografts
Colorectal cancer (CRC) is the second most common cancer in Europe and a leading cause of death worldwide. Patient-derived xenograft (PDX) models maintain complex intratumoral biology and heterogeneity and therefore remain the platform of choice for translational drug discovery. In this study, we im...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313970/ https://www.ncbi.nlm.nih.gov/pubmed/30662905 http://dx.doi.org/10.1155/2018/2954208 |