AICAR-Induced AMPK Activation Inhibits the Noncanonical NF-κB Pathway to Attenuate Liver Injury and Fibrosis in BDL Rats

BACKGROUND: To evaluate the AMP-activated protein kinase- (AMPK-) mediated signaling and NF-κB-related inflammatory pathways that contribute to cholestatic diseases in the bile duct ligation (BDL) rat model of chronic cholestasis and verify the protective role of 5-Aminoimidazole-4-carboxamide1-β-D-...

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Detalles Bibliográficos
Autores principales: Zhu, Haoyang, Chai, Yichao, Dong, Dinghui, Zhang, Nana, Liu, Wenyan, Ma, Tao, Wu, Rongqian, Lv, Yi, Hu, Liangshuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314002/
https://www.ncbi.nlm.nih.gov/pubmed/30662889
http://dx.doi.org/10.1155/2018/6181432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314002/
https://www.ncbi.nlm.nih.gov/pubmed/30662889
http://dx.doi.org/10.1155/2018/6181432

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