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Mechanisms of artemisinin resistance in Plasmodium falciparum malaria

Artemisinin-based combination therapies (ACTs) have substantially reduced worldwide malaria burden and deaths. But malaria parasites have become resistant to artemisinins. Prior studies suggested two different molecular pathways of artemisinin-resistance. Here we unify recent findings into a single...

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Detalles Bibliográficos
Autores principales: Suresh, Niraja, Haldar, Kasturi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314025/
https://www.ncbi.nlm.nih.gov/pubmed/30077118
http://dx.doi.org/10.1016/j.coph.2018.06.003