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Two clusters of residues contribute to the activity and substrate specificity of Fm1, a bifunctional oleate and linoleate desaturase of fungal origin

Polyunsaturated fatty acids (PUFAs) have important industrial, physiological, and nutritional properties. Plants use the sequential activities of FAD2 and FAD3 desaturases to convert 18:1Δ9 to the important PUFA 18:3Δ9,12,15, whereas the fungus Fusarium verticillioides 7600 uses the bifunctional des...

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Detalles Bibliográficos
Autores principales: Cai, Yuanheng, Yu, Xiao-Hong, Liu, Qun, Liu, Chang-Jun, Shanklin, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314118/
https://www.ncbi.nlm.nih.gov/pubmed/30348899
http://dx.doi.org/10.1074/jbc.RA118.005972