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Hormone-control regions mediate steroid receptor–dependent genome organization

In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. Here we further describe that responsive TADs contain 20- to 100-kb-long clusters of intermingled...

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Detalles Bibliográficos
Autores principales: Le Dily, François, Vidal, Enrique, Cuartero, Yasmina, Quilez, Javier, Nacht, A. Silvina, Vicent, Guillermo P., Carbonell-Caballero, José, Sharma, Priyanka, Villanueva-Cañas, José Luis, Ferrari, Roberto, De Llobet, Lara Isabel, Verde, Gaetano, Wright, Roni H.G., Beato, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314164/
https://www.ncbi.nlm.nih.gov/pubmed/30552103
http://dx.doi.org/10.1101/gr.243824.118