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Hormone-control regions mediate steroid receptor–dependent genome organization
In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. Here we further describe that responsive TADs contain 20- to 100-kb-long clusters of intermingled...
Autores principales: | Le Dily, François, Vidal, Enrique, Cuartero, Yasmina, Quilez, Javier, Nacht, A. Silvina, Vicent, Guillermo P., Carbonell-Caballero, José, Sharma, Priyanka, Villanueva-Cañas, José Luis, Ferrari, Roberto, De Llobet, Lara Isabel, Verde, Gaetano, Wright, Roni H.G., Beato, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314164/ https://www.ncbi.nlm.nih.gov/pubmed/30552103 http://dx.doi.org/10.1101/gr.243824.118 |
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