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Streptomyces avermitilis industrial strain as cell factory for Ivermectin B1a production

Ivermectin, a kind of valuable derivatives of Avermectin, is distinct from Avermectin due to the saturated bond at C22—C23 position. Combinatorial biosynthesis of Ivermectins based on Avermectins biosynthetic gene cluster (ave) has been achieved recently, while the establishment of an Ivermectin hom...

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Detalles Bibliográficos
Autores principales: Deng, Qian, Xiao, Liqiongzi, Liu, Yang, Zhang, Lixin, Deng, Zixin, Zhao, Changming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314238/
https://www.ncbi.nlm.nih.gov/pubmed/30623120
http://dx.doi.org/10.1016/j.synbio.2018.12.003