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CD4(+) CD25(+) regulatory T cells promote hepatocellular carcinoma invasion via TGF-β1-induced epithelial–mesenchymal transition

BACKGROUND: CD4(+) CD25(+) regulatory T cells (Tregs), a crucial component of the infiltration of immune cells in tumor microenvironment, are associated with progression and metastasis of hepatocellular carcinoma (HCC). METHODS: The mechanism of Tregs in the invasion and metastasis of HCC was invest...

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Detalles Bibliográficos
Autores principales: Shi, Chunying, Chen, Ying, Chen, Yaodong, Yang, Yuchuan, Bing, Wang, Qi, Jiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314313/
https://www.ncbi.nlm.nih.gov/pubmed/30643426
http://dx.doi.org/10.2147/OTT.S172417