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Evaluating ivosidenib for the treatment of relapsed/refractory AML: design, development, and place in therapy
Improvements in the last decade in understanding the molecular mechanisms underlying acute myeloid leukemia (AML) have emphasized that treatment regimens should be personalized with agents that can selectively target genetic abnormalities if present. Neomorphic mutations in isoform 1 of isocitrate d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314316/ https://www.ncbi.nlm.nih.gov/pubmed/30643428 http://dx.doi.org/10.2147/OTT.S182443 |