Sarcomere length–dependent effects on Ca(2+)-troponin regulation in myocardium expressing compliant titin

Cardiac performance is tightly regulated at the cardiomyocyte level by sarcomere length, such that increases in sarcomere length lead to sharply enhanced force generation at the same Ca(2+) concentration. Length-dependent activation of myofilaments involves dynamic and complex interactions between a...

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Detalles Bibliográficos
Autores principales: Li, King-Lun, Methawasin, Mei, Tanner, Bertrand C.W., Granzier, Henk L., Solaro, R. John, Dong, Wen-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314383/
https://www.ncbi.nlm.nih.gov/pubmed/30523116
http://dx.doi.org/10.1085/jgp.201812218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314383/
https://www.ncbi.nlm.nih.gov/pubmed/30523116
http://dx.doi.org/10.1085/jgp.201812218

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