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Spontaneous transitions of actin-bound tropomyosin toward blocked and closed states
After muscle contraction, myosin cross-bridge heads detach from thin actin filaments during relaxation. Structural and kinetic data of cross-bridge–thin filament interactions have shown that tropomyosin’s position on F-actin is biased toward the blocked or closed states when myosin detaches. It is n...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314389/ https://www.ncbi.nlm.nih.gov/pubmed/30442774 http://dx.doi.org/10.1085/jgp.201812188 |