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Safety, tolerability, and immunogenicity of a novel 4-antigen Staphylococcus aureus vaccine (SA4Ag) in healthy Japanese adults

A novel Staphylococcus aureus 4-antigen vaccine (SA4Ag) is under development, comprising capsular polysaccharide serotypes 5 and 8 (CP5 and CP8) conjugated to CRM(197), recombinant protein clumping factor A (rmClfA), and recombinant manganese transporter protein C (MntC). We evaluated SA4Ag safety,...

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Detalles Bibliográficos
Autores principales: Inoue, Megumi, Yonemura, Takuma, Baber, James, Shoji, Yasuko, Aizawa, Masakazu, Cooper, David, Eiden, Joseph, Gruber, William C., Jansen, Kathrin U., Anderson, Annaliesa S., Gurtman, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314418/
https://www.ncbi.nlm.nih.gov/pubmed/30084709
http://dx.doi.org/10.1080/21645515.2018.1496764