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Biliary Atresia Relevant Human Induced Pluripotent Stem Cells Recapitulate Key Disease Features in a Dish

Biliary atresia (BA) is the most common cause of pediatric end-stage liver disease and the etiology is poorly understood. There is no effective therapy for BA partly due to lack of human BA models. Towards developing in vitro human models of BA, disease-specific induced pluripotent stem cells (iPSCs...

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Detalles Bibliográficos
Autores principales: Tian, Lipeng, Ye, Zhaohui, Kafka, Kim, Stewart, Dylan, Anders, Robert, Schwarz, Kathleen B., Jang, Yoon-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314509/
https://www.ncbi.nlm.nih.gov/pubmed/30358741
http://dx.doi.org/10.1097/MPG.0000000000002187