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Viral MHCI inhibition evades tissue-resident memory T cell formation and responses

Tissue-resident memory CD8(+) T cells (T(RM)s) confer rapid protection and immunity against viral infections. Many viruses have evolved mechanisms to inhibit MHCI presentation in order to evade CD8(+) T cells, suggesting that these mechanisms may also apply to T(RM)-mediated protection. However, the...

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Detalles Bibliográficos
Autores principales: Lauron, Elvin J., Yang, Liping, Harvey, Ian B., Sojka, Dorothy K., Williams, Graham D., Paley, Michael A., Bern, Michael D., Park, Eugene, Victorino, Francisco, Boon, Adrianus C.M., Yokoyama, Wayne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314518/
https://www.ncbi.nlm.nih.gov/pubmed/30559127
http://dx.doi.org/10.1084/jem.20181077