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3D genomic architecture reveals that neocentromeres associate with heterochromatin regions

The centromere is an important genomic locus for chromosomal segregation. Although the centromere is specified by sequence-independent epigenetic mechanisms in most organisms, it is usually composed of highly repetitive sequences, which associate with heterochromatin. We have previously generated va...

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Detalles Bibliográficos
Autores principales: Nishimura, Kohei, Komiya, Masataka, Hori, Tetsuya, Itoh, Takehiko, Fukagawa, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314543/
https://www.ncbi.nlm.nih.gov/pubmed/30396998
http://dx.doi.org/10.1083/jcb.201805003