Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons

Axonal transport is required for neuronal development and survival. Transport from the axon to the soma is driven by the molecular motor cytoplasmic dynein, yet it remains unclear how dynein is spatially and temporally regulated. We find that the dynein effector Hook1 mediates transport of TrkB–BDNF...

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Detalles Bibliográficos
Autores principales: Olenick, Mara A., Dominguez, Roberto, Holzbaur, Erika L.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314548/
https://www.ncbi.nlm.nih.gov/pubmed/30373907
http://dx.doi.org/10.1083/jcb.201805016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314548/
https://www.ncbi.nlm.nih.gov/pubmed/30373907
http://dx.doi.org/10.1083/jcb.201805016

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