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HGF-induced migration depends on the PI(3,4,5)P(3)-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1

Differential inclusion or skipping of microexons is an increasingly recognized class of alternative splicing events. However, the functional significance of microexons and their contribution to signaling diversity is poorly understood. The Met receptor tyrosine kinase (RTK) modulates invasive growth...

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Detalles Bibliográficos
Autores principales: Ratcliffe, Colin D.H., Siddiqui, Nadeem, Coelho, Paula P., Laterreur, Nancy, Cookey, Tumini N., Sonenberg, Nahum, Park, Morag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314551/
https://www.ncbi.nlm.nih.gov/pubmed/30404949
http://dx.doi.org/10.1083/jcb.201804106