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A C5a-Immunoglobulin complex in chronic lymphocytic leukemia patients is associated with decreased complement activity
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. The therapeutic approach to CLL includes chemotherapeutic regimens and immunotherapy. Complement-mediated cytotoxicity, which is one of the mechanisms activated by the therapeutic monoclonal antibodies, depend...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314568/ https://www.ncbi.nlm.nih.gov/pubmed/30601845 http://dx.doi.org/10.1371/journal.pone.0209024 |