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A C5a-Immunoglobulin complex in chronic lymphocytic leukemia patients is associated with decreased complement activity

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. The therapeutic approach to CLL includes chemotherapeutic regimens and immunotherapy. Complement-mediated cytotoxicity, which is one of the mechanisms activated by the therapeutic monoclonal antibodies, depend...

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Detalles Bibliográficos
Autores principales: Michelis, Regina, Tadmor, Tamar, Barhoum, Masad, Shehadeh, Mona, Shvidel, Lev, Aviv, Ariel, Stemer, Galia, Dally, Najib, Rahimi-Levene, Naomi, Yuklea, Mona, Braester, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314568/
https://www.ncbi.nlm.nih.gov/pubmed/30601845
http://dx.doi.org/10.1371/journal.pone.0209024