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tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis

Translocation moves the tRNA(2)•mRNA module directionally through the ribosome during the elongation phase of protein synthesis. Although translocation is known to entail large conformational changes within both the ribosome and tRNA substrates, the orchestrated events that ensure the speed and fide...

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Detalles Bibliográficos
Autores principales: Flis, Julia, Holm, Mikael, Rundlet, Emily J., Loerke, Justus, Hilal, Tarek, Dabrowski, Marylena, Bürger, Jörg, Mielke, Thorsten, Blanchard, Scott C., Spahn, Christian M.T., Budkevich, Tatyana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314685/
https://www.ncbi.nlm.nih.gov/pubmed/30517857
http://dx.doi.org/10.1016/j.celrep.2018.11.040