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Improving the metabolic fidelity of cancer models with a physiological cell culture medium

Currently available cell culture media may not reproduce the in vivo metabolic environment of tumors. To demonstrate this, we compared the effects of a new physiological medium, Plasmax, with commercial media. We prove that the disproportionate nutrient composition of commercial media imposes metabo...

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Detalles Bibliográficos
Autores principales: Vande Voorde, Johan, Ackermann, Tobias, Pfetzer, Nadja, Sumpton, David, Mackay, Gillian, Kalna, Gabriela, Nixon, Colin, Blyth, Karen, Gottlieb, Eyal, Tardito, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314821/
https://www.ncbi.nlm.nih.gov/pubmed/30613774
http://dx.doi.org/10.1126/sciadv.aau7314