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Improving the metabolic fidelity of cancer models with a physiological cell culture medium
Currently available cell culture media may not reproduce the in vivo metabolic environment of tumors. To demonstrate this, we compared the effects of a new physiological medium, Plasmax, with commercial media. We prove that the disproportionate nutrient composition of commercial media imposes metabo...
Autores principales: | Vande Voorde, Johan, Ackermann, Tobias, Pfetzer, Nadja, Sumpton, David, Mackay, Gillian, Kalna, Gabriela, Nixon, Colin, Blyth, Karen, Gottlieb, Eyal, Tardito, Saverio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314821/ https://www.ncbi.nlm.nih.gov/pubmed/30613774 http://dx.doi.org/10.1126/sciadv.aau7314 |
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