MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection

Mast cells (MCs) are strategically distributed at barrier sites and prestore various immunocyte-recruiting cytokines, making them ideal targets for selective activation to treat peripheral infections. Here, we report that topical treatment with mastoparan, a peptide MC activator (MCA), enhances clea...

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Detalles Bibliográficos
Autores principales: Arifuzzaman, Mohammad, Mobley, Yuvon R., Choi, Hae Woong, Bist, Pradeep, Salinas, Cristina A., Brown, Zachary D., Chen, Swaine L., Staats, Herman F., Abraham, Soman N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314830/
https://www.ncbi.nlm.nih.gov/pubmed/30613778
http://dx.doi.org/10.1126/sciadv.aav0216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314830/
https://www.ncbi.nlm.nih.gov/pubmed/30613778
http://dx.doi.org/10.1126/sciadv.aav0216

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