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HDAC6 Regulates the MRTF-A/SRF Axis and Vascular Smooth Muscle Cell Plasticity

Cellular plasticity is fundamental in biology and disease. Vascular smooth muscle cell (SMC) dedifferentiation (loss of contractile proteins) initiates and perpetrates vascular pathologies such as restenosis. Contractile gene expression is governed by the master transcription factor, serum response...

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Detalles Bibliográficos
Autores principales: Zhang, Mengxue, Urabe, Go, Little, Christopher, Wang, Bowen, Kent, Alycia M., Huang, Yitao, Kent, K. Craig, Guo, Lian-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314972/
https://www.ncbi.nlm.nih.gov/pubmed/30623138
http://dx.doi.org/10.1016/j.jacbts.2018.08.010