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HDAC6 Regulates the MRTF-A/SRF Axis and Vascular Smooth Muscle Cell Plasticity
Cellular plasticity is fundamental in biology and disease. Vascular smooth muscle cell (SMC) dedifferentiation (loss of contractile proteins) initiates and perpetrates vascular pathologies such as restenosis. Contractile gene expression is governed by the master transcription factor, serum response...
Autores principales: | Zhang, Mengxue, Urabe, Go, Little, Christopher, Wang, Bowen, Kent, Alycia M., Huang, Yitao, Kent, K. Craig, Guo, Lian-Wang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314972/ https://www.ncbi.nlm.nih.gov/pubmed/30623138 http://dx.doi.org/10.1016/j.jacbts.2018.08.010 |
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