∆(9)-Tetrahydrocannabinol, a major marijuana component, enhances the anesthetic effect of pentobarbital through the CB(1) receptor

PURPOSE: ∆(9)-Tetrahydrocannabinol (∆(9)-THC) and cannabidiol (CBD), major psychoactive constituents of marijuana, induce potentiation of pentobarbital-induced sleep in mice. We have elucidated the mechanism of enhancement of the anesthetic effect of pentobarbital by cannabinoids. METHODS: We carrie...

Descripción completa

Detalles Bibliográficos
Autores principales: Kimura, Toshiyuki, Takaya, Makiko, Usami, Noriyuki, Watanabe, Kazuhito, Yamamoto, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314990/
https://www.ncbi.nlm.nih.gov/pubmed/30636988
http://dx.doi.org/10.1007/s11419-018-0457-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314990/
https://www.ncbi.nlm.nih.gov/pubmed/30636988
http://dx.doi.org/10.1007/s11419-018-0457-2

Ejemplares similares