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Expression of α-synuclein is regulated in a neuronal cell type-dependent manner

α-Synuclein, the major component of Lewy bodies (LBs) and Lewy neurites (LNs), is expressed in presynapses under physiologically normal conditions and is involved in synaptic function. Abnormal intracellular aggregates of misfolded α-synuclein such as LBs and LNs are pathological hallmarks of synucl...

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Detalles Bibliográficos
Autores principales: Taguchi, Katsutoshi, Watanabe, Yoshihisa, Tsujimura, Atsushi, Tanaka, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315015/
https://www.ncbi.nlm.nih.gov/pubmed/30362073
http://dx.doi.org/10.1007/s12565-018-0464-8