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Inhibition of SIRT2 limits tumour angiogenesis via inactivation of the STAT3/VEGFA signalling pathway

Mounting evidence has demonstrated that angiogenesis plays an important role in tumour progression. However, the key regulators in tumour angiogenesis remain unclear. Recently, emerging reports have indicated that SIRT2 plays critical roles in proliferation, metastasis and tumourigenesis in diverse...

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Detalles Bibliográficos
Autores principales: Hu, Fuqing, Sun, Xuling, Li, Geng, Wu, Qi, Chen, Yaqi, Yang, Xi, Luo, Xuelai, Hu, Junbo, Wang, Guihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315023/
https://www.ncbi.nlm.nih.gov/pubmed/30584257
http://dx.doi.org/10.1038/s41419-018-1260-z