Epigenetic silencing of ZNF132 mediated by methylation-sensitive Sp1 binding promotes cancer progression in esophageal squamous cell carcinoma

Epigenetic alteration of tumor suppression gene is one of the most significant indicators in human esophageal squamous cell carcinoma (ESCC). In this study, we identified a novel ESCC hypermethylation biomarker ZNF132 by integrative computational analysis to comprehensive genome-wide DNA methylation...

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Detalles Bibliográficos
Autores principales: Jiang, Dong, He, Zhenglei, Wang, Chenji, Zhou, Yinghui, Li, Fang, Pu, Weilin, Zhang, Xueqing, Feng, Xulong, Zhang, Meng, Yecheng, Xinyue, Xu, Yunyun, Jin, Li, Guo, Shicheng, Wang, Jiucun, Wang, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315024/
https://www.ncbi.nlm.nih.gov/pubmed/30578410
http://dx.doi.org/10.1038/s41419-018-1236-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315024/
https://www.ncbi.nlm.nih.gov/pubmed/30578410
http://dx.doi.org/10.1038/s41419-018-1236-z

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