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DR-region of Na(+)/K(+) ATPase is a target to treat excitotoxicity and stroke

Na(+)/K(+) ATPase (NKA) is important in maintaining cellular functions. We found that loss of NKA activities in NKAα1(+/−) mice is associated with increased susceptibility to ischemic injuries following transient middle cerebral artery occlusion (tMCAO). This is corroborated by the neuroprotective e...

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Detalles Bibliográficos
Autores principales: Shi, Meimei, Cao, Lei, Cao, Xu, Zhu, Mengyuan, Zhang, Xingzhou, Wu, Zhiyuan, Xiong, Siping, Xie, Zhizhong, Yang, Yong, Chen, Jingyu, Wong, Peter T. H., Bian, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315034/
https://www.ncbi.nlm.nih.gov/pubmed/30584244
http://dx.doi.org/10.1038/s41419-018-1230-5