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Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells

Autophagy occurs at a basal level in all eukaryotic cells and may support cell survival or activate death pathways. Due to its pathophysiologic significance, the autophagic machinery is a promising target for the development of multiple approaches for anti-neoplastic agents. We have recently describ...

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Detalles Bibliográficos
Autores principales: Zecchini, Silvia, Proietti Serafini, Francesca, Catalani, Elisabetta, Giovarelli, Matteo, Coazzoli, Marco, Di Renzo, Ilaria, De Palma, Clara, Perrotta, Cristiana, Clementi, Emilio, Buonanno, Federico, Ortenzi, Claudio, Marcantoni, Enrico, Taddei, Anna Rita, Picchietti, Simona, Fausto, Anna Maria, Cervia, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315039/
https://www.ncbi.nlm.nih.gov/pubmed/30584259
http://dx.doi.org/10.1038/s41419-018-1254-x