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Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells
Autophagy occurs at a basal level in all eukaryotic cells and may support cell survival or activate death pathways. Due to its pathophysiologic significance, the autophagic machinery is a promising target for the development of multiple approaches for anti-neoplastic agents. We have recently describ...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315039/ https://www.ncbi.nlm.nih.gov/pubmed/30584259 http://dx.doi.org/10.1038/s41419-018-1254-x |