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Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility

Living organisms are constantly exposed to DNA damage stress caused by endogenous and exogenous events. Eukaryotic cells have evolutionarily conserved DNA damage checkpoint surveillance systems. We previously reported that a unique transcription factor, Bdr1, whose expression is strongly induced by...

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Detalles Bibliográficos
Autores principales: Jung, Kwang-Woo, Lee, Yeonseon, Huh, Eun Young, Lee, Soo Chan, Lim, Sangyong, Bahn, Yong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315099/
https://www.ncbi.nlm.nih.gov/pubmed/30602579
http://dx.doi.org/10.1128/mBio.01726-18