Cargando…
Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility
Living organisms are constantly exposed to DNA damage stress caused by endogenous and exogenous events. Eukaryotic cells have evolutionarily conserved DNA damage checkpoint surveillance systems. We previously reported that a unique transcription factor, Bdr1, whose expression is strongly induced by...
Autores principales: | Jung, Kwang-Woo, Lee, Yeonseon, Huh, Eun Young, Lee, Soo Chan, Lim, Sangyong, Bahn, Yong-Sun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315099/ https://www.ncbi.nlm.nih.gov/pubmed/30602579 http://dx.doi.org/10.1128/mBio.01726-18 |
Ejemplares similares
-
CTP sensing and Mec1(ATR)-Rad53(CHK1/CHK2) mediate a two-layered response to inhibition of glutamine metabolism
por: Ajazi, Arta, et al.
Publicado: (2022) -
The Rad53(CHK1/CHK2)-Spt21(NPAT) and Tel1(ATM) axes couple glucose tolerance to histone dosage and subtelomeric silencing
por: Bruhn, Christopher, et al.
Publicado: (2020) -
Fungal infections: Pathogenesis, antifungals and alternate treatment approaches
por: Reddy, G.Kiran Kumar, et al.
Publicado: (2022) -
CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling
por: Narayanaswamy, Pavan B, et al.
Publicado: (2016) -
Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells
por: Zhao, Jianyun, et al.
Publicado: (2016)