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Systemic Factors During Metabolic Disease Progression Contribute to the Functional Decline of Adipose Tissue-Derived Mesenchymal Stem Cells in Reproductive Aged Females

It is known that advanced metabolic disorders such as type 2 diabetes compromise the functional and regenerative capacity of endogenous adipose-tissue resident stem cells (ADSCs). It is, however, still unclear at which stage of disease progression ADSCs become compromised and whether systemic factor...

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Detalles Bibliográficos
Autores principales: Seboko, Ascentia M., Conradie, M. M., Kruger, M. J., Ferris, William Frank, Conradie, Magda, van de Vyver, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315119/
https://www.ncbi.nlm.nih.gov/pubmed/30631282
http://dx.doi.org/10.3389/fphys.2018.01812