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Metoprolol, N-Acetylcysteine, and Escitalopram Prevents Chronic Unpredictable Mild Stress-Induced Depression by Inhibition of Endoplasmic Reticulum Stress

Background: Endoplasmic reticulum stress (ERS) has been recently suggested to be activated in the major depressive disorder (MDD). However, whether ERS is a potential therapeutic target for MDD is largely unknown. Here we attempted to assess the preventive effect of metoprolol (MET), N-acetylcystein...

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Detalles Bibliográficos
Autores principales: Yang, Lixia, Zheng, Lei, Wan, Yan, Chen, Zhenghong, Li, Peifan, Wang, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315151/
https://www.ncbi.nlm.nih.gov/pubmed/30631289
http://dx.doi.org/10.3389/fpsyt.2018.00696