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Design of Peptide-Based Nanovaccines Targeting Leading Antigens From Gynecological Cancers to Induce HLA-A2.1 Restricted CD8(+) T Cell Responses

Gynecological cancers are a leading cause of mortality in women. CD8(+) T cell immunity largely correlates with enhanced survival, whereas inflammation is associated with poor prognosis. Previous studies have shown polystyrene nanoparticles (PSNPs) are biocompatible, do not induce inflammation and w...

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Detalles Bibliográficos
Autores principales: Xiang, Sue D., Wilson, Kirsty L., Goubier, Anne, Heyerick, Arne, Plebanski, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315164/
https://www.ncbi.nlm.nih.gov/pubmed/30631324
http://dx.doi.org/10.3389/fimmu.2018.02968