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Metabolic Dependencies in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDA) is a highly lethal cancer with a long-term survival rate under 10%. Available cytotoxic chemotherapies have significant side effects, and only marginal therapeutic efficacy. FDA approved drugs currently used against PDA target DNA metabolism and DNA integrity....

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Detalles Bibliográficos
Autores principales: Vaziri-Gohar, Ali, Zarei, Mahsa, Brody, Jonathan R., Winter, Jordan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315177/
https://www.ncbi.nlm.nih.gov/pubmed/30631752
http://dx.doi.org/10.3389/fonc.2018.00617