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The Contribution of Co-signaling Pathways to Anti-malarial T Cell Immunity

Plasmodium spp., the causative agent of malaria, caused 212 million infections in 2016 with 445,000 deaths, mostly in children. Adults acquire enough immunity to prevent clinical symptoms but never develop sterile immunity. The only vaccine for malaria, RTS,S, shows promising protection of a limited...

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Detalles Bibliográficos
Autores principales: Faleiro, Rebecca, Karunarathne, Deshapriya S., Horne-Debets, Joshua M., Wykes, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315188/
https://www.ncbi.nlm.nih.gov/pubmed/30631323
http://dx.doi.org/10.3389/fimmu.2018.02926