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Losartan Prevents Maladaptive Auditory-Somatosensory Plasticity After Hearing Loss via Transforming Growth Factor-β Signaling Suppression

OBJECTIVES: Hearing loss disrupts the balance of auditory-somatosensory inputs in the cochlear nucleus (CN) of the brainstem, which has been suggested to be a mechanism of tinnitus. This disruption results from maladaptive auditory-somatosensory plasticity, which is a form of axonal sprouting. Axona...

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Detalles Bibliográficos
Autores principales: Mun, Seog-Kyun, Han, Kyu-Hee, Baek, Jong Tae, Ahn, Suk-Won, Cho, Hyun Sang, Chang, Mun Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315212/
https://www.ncbi.nlm.nih.gov/pubmed/30021416
http://dx.doi.org/10.21053/ceo.2018.00542