Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate

An intricate link is becoming apparent between metabolism and cellular identities. Here, we explore the basis for such a link in an in vitro model for early mouse embryonic development: from naïve pluripotency to the specification of primordial germ cells (PGCs). Using single‐cell RNA‐seq with stati...

Descripción completa

Detalles Bibliográficos
Autores principales: Tischler, Julia, Gruhn, Wolfram H, Reid, John, Allgeyer, Edward, Buettner, Florian, Marr, Carsten, Theis, Fabian, Simons, Ben D, Wernisch, Lorenz, Surani, M Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315289/
https://www.ncbi.nlm.nih.gov/pubmed/30257965
http://dx.doi.org/10.15252/embj.201899518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315289/
https://www.ncbi.nlm.nih.gov/pubmed/30257965
http://dx.doi.org/10.15252/embj.201899518

Ejemplares similares