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Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1‐integrin

Control of synapse number and function in the developing central nervous system is critical to the formation of neural circuits. Astrocytes play a key role in this process by releasing factors that promote the formation of excitatory synapses. Astrocyte‐secreted thrombospondins (TSPs) induce the for...

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Detalles Bibliográficos
Autores principales: Fossati, Giuliana, Pozzi, Davide, Canzi, Alice, Mirabella, Filippo, Valentino, Sonia, Morini, Raffaella, Ghirardini, Elsa, Filipello, Fabia, Moretti, Milena, Gotti, Cecilia, Annis, Douglas S, Mosher, Deane F, Garlanda, Cecilia, Bottazzi, Barbara, Taraboletti, Giulia, Mantovani, Alberto, Matteoli, Michela, Menna, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315291/
https://www.ncbi.nlm.nih.gov/pubmed/30396995
http://dx.doi.org/10.15252/embj.201899529