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Fluorogenic RNA Aptamers: A Nano-platform for Fabrication of Simple and Combinatorial Logic Gates

RNA aptamers that bind non-fluorescent dyes and activate their fluorescence are highly sensitive, nonperturbing, and convenient probes in the field of synthetic biology. These RNA molecules, referred to as light-up aptamers, operate as molecular nanoswitches that alter folding and fluorescence funct...

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Detalles Bibliográficos
Autores principales: Goldsworthy, Victoria, LaForce, Geneva, Abels, Seth, Khisamutdinov, Emil F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315349/
https://www.ncbi.nlm.nih.gov/pubmed/30486495
http://dx.doi.org/10.3390/nano8120984