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Constrained α-Helical Peptides as Inhibitors of Protein-Protein and Protein-DNA Interactions
Intracellular regulatory pathways are replete with protein-protein and protein-DNA interactions, offering attractive targets for therapeutic interventions. So far, most drugs are targeted toward enzymes and extracellular receptors. Protein-protein and protein-DNA interactions have long been consider...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315407/ https://www.ncbi.nlm.nih.gov/pubmed/30567318 http://dx.doi.org/10.3390/biomedicines6040118 |