Aptamer-iRNAs as Therapeutics for Cancer Treatment

Aptamers are single-stranded oligonucleotides (ssDNA or ssRNA) that bind and recognize their targets with high affinity and specificity due to their complex tertiary structure. Aptamers are selected by a method called SELEX (Systematic Evolution of Ligands by EXponential enrichment). This method has...

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Detalles Bibliográficos
Autores principales: Soldevilla, Mario M., Meraviglia-Crivelli de Caso, Daniel, Menon, Ashwathi P., Pastor, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315413/
https://www.ncbi.nlm.nih.gov/pubmed/30340426
http://dx.doi.org/10.3390/ph11040108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315413/
https://www.ncbi.nlm.nih.gov/pubmed/30340426
http://dx.doi.org/10.3390/ph11040108

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