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Aptamer-iRNAs as Therapeutics for Cancer Treatment
Aptamers are single-stranded oligonucleotides (ssDNA or ssRNA) that bind and recognize their targets with high affinity and specificity due to their complex tertiary structure. Aptamers are selected by a method called SELEX (Systematic Evolution of Ligands by EXponential enrichment). This method has...
Autores principales: | Soldevilla, Mario M., Meraviglia-Crivelli de Caso, Daniel, Menon, Ashwathi P., Pastor, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315413/ https://www.ncbi.nlm.nih.gov/pubmed/30340426 http://dx.doi.org/10.3390/ph11040108 |
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