Combining Optical Approaches with Human Inducible Pluripotent Stem Cells in G Protein-Coupled Receptor Drug Screening and Development

Drug discovery for G protein-coupled receptors (GPCRs) stands at an interesting juncture. Screening programs are slowly moving away from model heterologous cell systems such as human embryonic kidney (HEK) 293 cells to more relevant cellular, tissue and whole animal platforms. Investigators are now...

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Detalles Bibliográficos
Autores principales: Bourque, Kyla, Jones-Tabah, Jace, Mnasri, Nourhen, Martin, Ryan D., Hébert, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315445/
https://www.ncbi.nlm.nih.gov/pubmed/30567417
http://dx.doi.org/10.3390/biom8040180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315445/
https://www.ncbi.nlm.nih.gov/pubmed/30567417
http://dx.doi.org/10.3390/biom8040180

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