Iron as a Therapeutic Target in HFE-Related Hemochromatosis: Usual and Novel Aspects

Genetic hemochromatosis is an iron overload disease that is mainly related to the C282Y mutation in the HFE gene. This gene controls the expression of hepcidin, a peptide secreted in plasma by the liver and regulates systemic iron distribution. Homozygous C282Y mutation induces hepcidin deficiency,...

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Detalles Bibliográficos
Autores principales: Loréal, Olivier, Cavey, Thibault, Robin, François, Kenawi, Moussa, Guggenbuhl, Pascal, Brissot, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315470/
https://www.ncbi.nlm.nih.gov/pubmed/30486249
http://dx.doi.org/10.3390/ph11040131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315470/
https://www.ncbi.nlm.nih.gov/pubmed/30486249
http://dx.doi.org/10.3390/ph11040131

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