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Iron as a Therapeutic Target in HFE-Related Hemochromatosis: Usual and Novel Aspects
Genetic hemochromatosis is an iron overload disease that is mainly related to the C282Y mutation in the HFE gene. This gene controls the expression of hepcidin, a peptide secreted in plasma by the liver and regulates systemic iron distribution. Homozygous C282Y mutation induces hepcidin deficiency,...
Autores principales: | Loréal, Olivier, Cavey, Thibault, Robin, François, Kenawi, Moussa, Guggenbuhl, Pascal, Brissot, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315470/ https://www.ncbi.nlm.nih.gov/pubmed/30486249 http://dx.doi.org/10.3390/ph11040131 |
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