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The STAT3/Slug Axis Enhances Radiation-Induced Tumor Invasion and Cancer Stem-like Properties in Radioresistant Glioblastoma

Glioblastoma multiforme (GBM) requires radiotherapy (RT) as a part of definitive management strategy. RT is highly effective, destroying cancer cells that may exist around the surgical tumor bed. However, GBM still has a poor prognosis and a high local recurrence rate after RT. Accumulating research...

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Detalles Bibliográficos
Autores principales: Lin, Jang-Chun, Tsai, Jo-Ting, Chao, Tsu-Yi, Ma, Hsin-I, Liu, Wei-Hsiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315497/
https://www.ncbi.nlm.nih.gov/pubmed/30551687
http://dx.doi.org/10.3390/cancers10120512